IIT Madras researchers develop AI tool to identify cancer-causing genes

Tags: Science and Technology

An Artificial Intelligence-based tool named 'PIVOT' has been developed by researchers from the Indian Institute of Technology Madras (IIT Madras).


  • PIVOT is designed to predict genes that are responsible for causing cancer.

  • This AI-based tool will help in developing strategies for personalised cancer treatment.

  • PIVOT is able to predict cancer-causing genes in patients.

  • The PIVOT tool was developed based on the machine learning model, which categorises genes as tumour oncogenes, suppressor genes or neutral genes.

  • It successfully predicted oncogenes as well as tumour-suppressor genes such as TP53, and PIK3CA.

  • How does this work?

  • PIVOT is a machine learning tool.

  • It uses a variety of data, including mutations and gene expression, to predict cancer-causing genes.

  • These genes are called driver genes.

  • It helps in formulating personalised cancer treatment strategies.

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